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The Global Pharmaceutical Industry is Accelerating; Aptorum Group Has Received Orphan Drug Designation from US FDA for Its SACT-1

27 7 月, 2022

HONG KONG, July 26, 2022 - (ACN Newswire) - The aging of the population is accelerating, pharmaceutical technology is constantly updating, and the development of the global pharmaceutical industry continues to accelerate. The pharmaceutical market is expected to maintain a growing trend. According to Frost & Sullivan, the global pharmaceutical market is expected to reach $1,711.4 billion by 2025. Aptorum Group Limited (Nasdaq: APM, Euronext Paris: APM) is a clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of therapeutic assets to treat diseases with unmet medical needs, particularly in oncology (including orphan oncology indications) and infectious diseases. The pipeline of Aptorum is also enriched through (i) the establishment of drug discovery platforms that enable the discovery of new therapeutics assets through, e.g. discovery and development of new small molecules and biologics, and systematic screening of existing approved drug molecules, etc.; and (ii) the co-development of a novel molecular-based rapid pathogen identification and detection diagnostics technology with Accelerate Technologies Pte Ltd, the commercialization arm of the Singapore's Agency for Science, Technology and Research. Currently, Aptorum Group's R&D pipelines cover the ALS family of drugs and the SACT family of drugs, covering such indications as drug-resistant Staphylococcus aureus (including MRSA), Gram-positive cocci, influenza A, COVID-19, orphan disease neuroblastoma and other cancers. Since the beginning of this year, Aptorum Group has accelerated its research and development (R&D), with major breakthroughs achieved in several pipelines under development. SACT-1, the Group's orally administered small molecule drug for the treatment of neuroblastoma, was granted its first patent by the United States Patent and Trademark Office (US PTO) in November 2021 and Orphan Drug Designation by the US Food and Drug Administration (FDA) at the beginning of this year. Meanwhile, the Group completed the Phase I clinical trial of SACT-1 in January this year and announced the finalized data in May. The data showed that SACT-1 had impressive safety and good tolerability making the later stages of SACT-1 promising. In addition, earlier in the year, the Group launched oncology and autoimmune discovery and development platform targeting unmet mutations and novel biomarkers, focusing on indications including non-small cell lung cancer ("NSCLC") and autoimmune diseases such as lupus, rheumatoid arthritis and inflammatory bowel diseases. In the meantime, the Group also completed a Phase I clinical trial for ALS-4, a first-in-class anti-virulence-based small molecule drug targeting infections caused by Staphylococcus aureus including MRSA. In the second quarter of this year, the Group's Rapid Pathogen Infectious Disease Liquid Biopsy Diagnostics ("RPIDD") was granted a patent by the US PTO, and the Group is spearheading the efforts in the ongoing clinical validation and pre-commercialisation preparation of the technology. Currently, the overall development prospect of the biopharmaceutical industry is promising. Aptorum Group is actively advancing its R&D projects. With its strong R&D capabilities and internal management capacity, it is expected to further enhance its business development, expand the room for enterprise development, and gain greater development opportunities in the biopharmaceutical industry.

ACN Newswire

IBI Group Announces FY2022 Annual Results, Steadfast Resilience Albeit Market Challenges

30 6 月, 2022

HONG KONG, Jun 30, 2022 - (ACN Newswire via SEAPRWire.com) - IBI Group Holdings Limited ("IBI" or the "Company", together with its subsidiaries as the "Group"; Stock Code: 1547), a publicly listed company that holds investments in companies focusing on the Built Environment, today announced its business results for the financial year ended 31 March 2022 ("FY2022").During the year under review, the Group recorded an income of approximately HK$405.9 million (FY2021: HK$556.7 million). Gross profit was approximately HK$68.0 million (FY2021: HK$79.4 million) and profit attributable to the owners of the Company was approximately HK$27.0 million compared with approximately HK$54.4 million from the previous financial year (which included a one-off gain of approximately HK$43.6 million generated from its strategic investments segment). Basic and diluted earnings per share was HK3.4 cents (FY2021: HK6.8 cents).The Group maintained a strong financial position with cash and cash equivalents of approximately HK$141.6 million (FY2021: HK$87.1 million) and no bank borrowings as at 31 March 2022. The Board has recommended payment of a final dividend of HK1.0 cent per share for the year ended 31 March 2022 (FY2021: HK4.0 cents).Business Review1. ContractingIBI provides world-class interior fitting out and building refurbishment services in Hong Kong and Macau, undertaking two main types of projects namely fitting-out projects and alteration and addition projects. Owing to its established reputation and proven track record, the Hong Kong component of the Company remained busy during FY2022 despite the continuing shadow cast by the Covid-19 pandemic, completing 11 fitting-out projects and being awarded 14 more. During the year under review, revenue from the segment totaled approximately HK$403.9 million (FY2021: HK$511.0 million) with segmental gross profit increasing by an exceptional 91.0% amounting to approximately HK$67.4 million. 2. Building SolutionsIn April 2020, IBI set up its subsidiary, Building Solutions Limited ("BSL"), a provider of products and services that enhance the performance and well-being of the built environment in order to provide modern, healthy and high-performing spaces for its occupants. During the year under review, BSL has been working diligently to develop the business and secure orders. The second year of its operations has shown significant penetration into the market, leading to improved sales figures. BSL has additionally secured distribution rights to a cutting-edge lighting product that has been very well received and will be reflected in the sales figures for the coming financial year. BSL registered a segment loss of approximately HK$2.7 million in FY2022.3. Strategic InvestmentsThe financial year was spent in part, divesting the Group of its earlier stock investments which had generated phenomenal returns in the previous reporting period. In addition, IBI's efforts were targeted toward property-related investment deals and these efforts have generated considerable early success. During the latter part of FY2022, the Group secured development land in Hokkaido, Japan located in close proximity to a future station of the planned Shinkansen high-speed rail line, and is now working with a local development specialist to establish the most efficient use of the land and the timing of the development. Moving forward, the Group will continue to look at potential investment opportunities. Subsequent to the financial reporting period, the Group recently acquired Adelaide Chambers, a building located in the heart of Dublin, Ireland. The investment is a period building with approximately 20,000 square feet of commercial office space and is a value-add proposition with improvements to be made, in both building upgrades and lease improvements, in order to increase the overall asset value and to secure additional profits for the Group.ProspectsHong Kong has now lifted many of the restrictions put in place during the pandemic and life is very quickly returning to normal. The Group is optimistic that Hong Kong will start to regain its full international status once the city's strict quarantine restrictions are further reduced, returning to more normal business activity levels along with stabilization of the market environment. Moving forward, the Group is confident that the capital allocated for its investment will be fully vested within the coming financial year.Mr. Neil Howard, Chairman and CEO of IBI, said, "Amid unprecedented challenges created by COVID-19 pandemic, we have remained steadfast and resilient in driving our growth and investment strategies. IBI is excited for the year ahead and believes that the business environment will move from strength to strength as we slowly transition into the pre-pandemic period. As a result of our strategic business decisions, IBI continued to deliver stable performance and we are extremely proud to be able to retain our full workforce during these challenging times. We are thrilled to see growth in our subsidiaries, especially BSL, and look forward to reporting significantly improved financials as it moves out of its infancy and into its development phase. Our FY2022 results are a testament to our ability to provide integrated, innovative solutions and we look forward to bringing stronger results and add long-term value to shareholders."About IBI Group Holdings Limited (stock code: 1547)IBI Group Holdings Limited is a publicly listed holding company on the Hong Kong Stock Exchange, focused on investments in the Built Environment. The Group's investments whilst principally centering around the role of contracting, including businesses providing an innovative, high-quality product and supply solutions across a diverse range of the built environment. Our mission is to deliver premium products, services and customer experiences with a strong influence on innovation, sustainability and wellness. For more information, please refer to IBI's website: https://ibighl.com/. Copyright 2022 ACN Newswire. All rights reserved. (via SEAPRWire)

JCN Newswire

Mazda Production and Sales Results for May 2022

30 6 月, 2022

HIROSHIMA, Japan, Jun 30, 2022 - (JCN Newswire via SEAPRWire.com) - Mazda Motor Corporation's production and sales results for May 2022 are summarized below.I. Production1. Domestic ProductionMazda's domestic production volume in May 2022 decreased 30.2% year on year due to decreased production of passenger vehicles.[Domestic production of key models in May 2022]CX-5: 16,879 units (down 15.9% year on year)CX-30: 4,893 units (up 42.1%)CX-9: 2,733 units (down 34.7%)2. Overseas ProductionMazda's overseas production volume in May 2022 decreased 10.6% year on year due to decreased production of passenger vehicles.[Overseas production of key models in May 2022]MAZDA3: 7,720 units (down 5.0% year on year)CX-30: 7,658 units (down 7.3%)MAZDA2: 3,698 units (down 28.6%)II. Domestic SalesMazda's domestic sales volume in May 2022 decreased 36.7% year on year due to decreased sales of passenger and commercial vehicles.Mazda's registered vehicle market share was 2.1% (down 1.3 points year on year), with a 2.3% share of the micro-mini segment (up 0.4 points) and a 2.2% total market share (down 0.6 points).[Domestic sales of key models in May 2022]MAZDA2: 848 units (down 36.9% year on year)CX-5: 813 units (down 2.0%)MAZDA3: 341 units (down 64.6%)III. ExportsMazda's export volume in May 2022 decreased 52.7% year on year due to decreased shipment to North America, Europe, Oceania and other regions.[Exports of key models in May 2022]CX-5: 11,274 units (down 46.2% year on year)CX-30: 2,350 units (down 38.7%)CX-9: 1,992 units (down 53.8%)IV. Global SalesMazda's global sales volume in May 2022 decreased 41.9% year on year due to decreased sales mainly in the U.S., China, Europe and other regions.[Global sales of key models in May 2022]CX-5: 21,392 units (down 45.3% year on year)CX-30: 12,379 units (down 41.6%)MAZDA3: 11,353 units (down 43.3%) Copyright 2022 JCN Newswire. All rights reserved. (via SEAPRWire)

JCN Newswire

Fujitsu Recognized as Winner of 2022 Microsoft Education Partner of the Year Award

29 6 月, 2022

TOKYO, Jun 29, 2022 - (JCN Newswire via SEAPRWire.com) - Fujitsu today announced that it has won the 2022 Microsoft Education Partner of the Year award. Fujitsu was honored among a global field of top Microsoft partners for demonstrating excellence in innovation and implementation of customer solutions based on Microsoft technology."Fujitsu is thrilled to be recognized by Microsoft for our contribution working with clients and partners in supporting over a million students across North America. This helped improve learning environments for students from all different backgrounds to reduce the disruption in education caused by COVID." said Cathy McCann, Vice President Head of Trusted Society, Uvance Unit, Fujitsu. "This initiative underlines the important role we believe technology and global companies, such as Fujitsu and Microsoft, can play by working together to support educators worldwide, as they strive to improve education equity and access for everyone."The Microsoft Partner of the Year Awards recognize Microsoft partners that have developed and delivered outstanding Microsoft-based applications, services and devices during the past year. Awards were classified in various categories, with honorees chosen from a set of more than 3,900 submitted nominations from more than 100 countries worldwide. Fujitsu was recognized for providing outstanding solutions and services in the Education category.In presenting this award, Microsoft recognizes Fujitsu for its ongoing efforts in North America and skill in working in collaboration with Microsoft and ISV community partners, in particular Follett School Solutions, to use Microsoft Azure services to produce outstanding outcomes for Fujitsu's education clients in Canada and the United States.At the height of the Covid-19 pandemic, Fujitsu leveraged its SIS to support tens of thousands of educators and over 1M students in North America. This helped to digitally transform administrative operations and completely reorganize classroom courses to be run online in a matter of days. This allowed teachers to introduce new services and provide continuity for all students and parents at a time of extraordinary uncertainty.Based on SIS, Fujitsu successfully implemented and manages "MyEducation BC," a province-wide service shared by teachers, school officials and by over 650,000 students and parents in over 2,000 schools in all 60 School Districts and many private schools across British Columbia. Another provincial service based on SIS, "MySchoolSask", supports all 27 School Divisions with 205,000 students across the Province of Saskatchewan. Despite sudden, unexpected changes and significant workload spikes on the SIS, both environments have performed without disruption, delivering full security and privacy compliance, as well as peace of mind to school administrators.Moving forward, Fujitsu will continue to promote partnerships with stakeholders, including public institutions, citizens, and business partners, focusing on innovative and reliable technologies to realize a "Trusted Society," one of Fujitsu's 7 Key Focus Areas under its global business brand Fujitsu Uvance to create a more sustainable world."I am honored to announce the winners and finalists of the 2022 Microsoft Partner of the Year Awards," said Nick Parker, corporate vice president of Global Partner Solutions at Microsoft. "These partners were outstanding among the exceptional pool of nominees and I'm continuously impressed by their innovative use of Microsoft Cloud technologies and the impact for their customers."Microsoft Partner of the Year Awards are announced annually prior to the company's global partner conference, Microsoft Inspire, which will take place on July 19-20 this year.Additional details on the 2022 awards are available on the Microsoft Partner Network blog: bit.ly/3y25ArR. The complete list of categories, winners and finalists can be found at https://partner.microsoft.com/en-us/inspire/awards.About FujitsuFujitsu's purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers in over 100 countries, our 124,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: Computing, Networks, AI, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.6 trillion yen (US$32 billion) for the fiscal year ended March 31, 2022 and remains the top digital services company in Japan by market share. Find out more: www.fujitsu.com. Copyright 2022 JCN Newswire. All rights reserved. (via SEAPRWire)

ACN Newswire

Nomination Opens for “Directors Of The Year Awards 2022”

22 6 月, 2022

HONG KONG, Jun 22, 2022 - (ACN Newswire via SEAPRWire.com) - The "Directors Of The Year Awards 2022" organised by The Hong Kong Institute of Directors ("HKIoD") is open for nomination now. Themed "From Resilience to Sustainability", the Awards this year recognises directors and boards capable of leading their companies in adapting to changes and, with outstanding governance thinking and practical strategies skills, taking their companies towards sustainable development in the ever-changing business environment.Dr Christopher To, Chairman of HKIoD, said, "Leadership in crisis calls for the ability to rethink and redefine some long-standing values or structure, and also the courage and strength to brave the uphill. In the at large uncertain environment now, we must keep learning, evolving, adapting and changing, to make sure the 'new normal' is a 'better normal'. Marking HKIoD's 25th Anniversary, this year's award is themed 'From Resilience to Sustainability', reflective of what we have learnt over the years. Resilience is the most important quality a company needs to survive in the ever-changing world and sustainability is the ultimate goal of every company. I hope all of you can nominate directors and boards standing out in these two aspects, that we may take as examples to inspire all in the business sector to excel."Mr Richard Ho, Chairman of 2022 Directors Awards Organising Committee, said, "When discussing the award theme this year, the Committee thought though the global scene is still unpredictable and challenging, it has become clearer. Thus, we decided to have 'From Resilience to Sustainability' as the theme easier to grasp. We hope to commend those outstanding leaders who braved the challenges from the pandemic and helped their companies achieve good results, and also to remind those in different sectors to set their eyes on long-term strategy and advance towards their sustainable development goal."Dr Carlye Tsui, CEO of HKIoD, said, "All of us, companies or individuals, have gotten used to staying clam in the turbulent environment. With our feet firmly on the ground, it is time that we head again towards our long-term targets. Directors, as leaders of a company, should be sensitive at all times to changes in the market and plan the 'next step' to take. For example, Web3.0 is the latest and a major trend likely to bring revolutionary changes in the near future to all of us. Business leaders who do not have a good understanding of it might just miss the opportunities that come with it. Offering diverse and innovative courses, HKIoD helps members refresh what has been learnt and acquire new knowledge, so that they may be ready any time to take their companies forward."Nomination for the Awards will close on 1 August 2022. On the Judging Panel are business leaders, professionals and regulatory body representatives in Hong Kong. The Directors Of The Year Awards 2022 recognise excellence in the following categories:Company Categories / Director Categories1. Listed Companies / 1. Executive Directors2. Non-Listed Companies / 2. Non-Executive Directors3. Statutory/Non-Profit-Distributing Organisations* / 3. BoardsNotes: *A non-profit-distributing organisation is defined as an organisation which profits are not distributed to its shareholders, members, directors, employees or any other persons, and with objectives including, but not limited to, charitable welfare, social service, health and medical care, education, research, trade and industrial alliance, professional advancement, self-help support, etc.The selection criteria for winners in the Individual Director Categories include: successful pursuit of strategic corporate business/non-profit functions, contribution to board effectiveness in strategic planning and monitoring of performance, implementing compliance, risk control and accountability measures, managing change and succession, and leadership and other attributes and qualities, including keen at continuing professional development, business ethics and other achievements. As for the Collective Board Categories, the judging criteria include: board composition, effectiveness in pursuing strategic corporate/non-profit functions, development and execution of strategic plans and monitoring of performance, implementing compliance, risk control and accountability measures, managing change and succession, development of the board, effectiveness of board committees, business ethics and other achievements.The Awards nomination form and related information are available on The Hong Kong Institute of Directors website www.hkiod.com.About Directors Of The Year AwardsLaunched in 2001, the Directors Of The Year Awards was the first of its kind organised in Asia. It is now an annual project of impact in the community. Its objectives are to recognise directors and board of directors for outstanding director practices and corporate governance, to publicise the significance of good corporate governance and to promote awareness of good corporate governance and director professionalism in Hong Kong. Nominations are open to the public. As good corporate governance is vital to all types of organisations, and professional practices from directors in all board roles are encouraged, the Awards recognise excellence in categories by company types, including listed companies, private companies and statutory/non-profit-distributing organisations, and categories by roles, including Executive Directors, Non-Executive Directors and Boards. For more details on the previous years' Awards, please visit http://www.hkiod.com/dya-awardees.html.About The Hong Kong Institute of DirectorsThe Hong Kong Institute of Directors is Hong Kong's premier body representing directors to foster the long-term success of companies through advocacy and standards-setting in corporate governance and professional development for directors. A non-profit-distributing organisation with membership consisting of directors from listed and non-listed companies, HKIoD is committed to providing directors with educational programmes and information service and establishing an influential voice in representing directors. With international perspectives and a multi-cultural environment, HKIoD conducts business in biliteracy and trilingualism. Website: http://www.hkiod.com.Media Enquiries:Strategic Public Relations GroupBrenda Chan +852 2114 4396 brenda.chan@sprg.com.hkChak Yau +852 2114 4395 chak.yau@sprg.com.hkFax: +852 2114 4948Directors Of The Year Awards 2022 Enquiries:The Hong Kong Institute of DirectorsOdessa So +852 2889 4988 odessa.so@hkiod.com Joanne Yam +852 2889 1414 joanne.yam@hkiod.comFax: +852 2889 9982 Copyright 2022 ACN Newswire. All rights reserved. (via SEAPRWire)

JCN Newswire

TOYOTA GAZOO Racing into Africa to defend Safari crown

17 6 月, 2022

TOKYO, Jun 17, 2022 - (JCN Newswire via SEAPRWire.com) - The TOYOTA GAZOO Racing World Rally Team heads to Safari Rally Kenya on June 23-26 with the goal of defending its crown on the iconic African event.2022 GR YARIS Rally1The Safari made a long-awaited comeback to the FIA World Rally Championship calendar in 2021 when Sebastien Ogier led a one-two finish for TOYOTA GAZOO Racing. Ogier is making Kenya his third WRC appearance of the 2022 season as the team targets a 10th victory on the event for the Japanese marque.The team's first priority is to return to the podium after a challenging previous round in Sardinia, although Kalle Rovanpera still left the Italian island having increased his drivers' championship lead to 55 points. Both Rovanpera and Elfyn Evans will be motivated for the trip to Kenya after experiencing its pitfalls on their debuts there last year. Takamoto Katsuta, on the other hand, travels back to the scene of his maiden podium finish (after finishing second to Ogier one year ago) as he looks to continue his 2022 scoring streak for TGR WRT Next Generation.Having previously featured incredibly long stages on roads that were still open to the public, today's Safari Rally runs to a format similar to other modern WRC rounds. Still, the drivers and cars face incredibly demanding gravel roads with some very rough and rocky sections, while the weather has the potential to dramatically change the conditions in a very short space of time.Shakedown takes place on Wednesday before the rally begins on Thursday lunchtime from capital city Nairobi, with the nearby Kasarani super special kicking off the competitive action. The rest of the weekend is centred around the service park on the shores of Lake Naivasha, around 100 kilometres to the north-west. Friday's repeated loop of three stages around the lake includes a brand new test, Geothermal, as well as the weekend's longest: the 31.25 kilometres of Kedong. Saturday takes place further north close to Lake Elmenteita with two passes of three familiar stages from 2021, although Soysambu has been extended and Elmenteita itself will be run in the opposite direction to before. A trio of stages south of Naivasha are all run twice to form Sunday's final day, including the new Narasha test and Hell's Gate, which hosts the rally-ending Power Stage.Quotes:Jari-Matti Latvala (Team Principal)"It was exciting to have the Safari Rally back on the calendar last year and even though the rally is very different to before, the spirit of the event is the same: it's more about endurance than outright speed. At one stage it looked like it would be difficult for us to even be on the podium and in the end we finished one-two. So again this year we need to be prepared for anything to happen, and it will be another big test for the Rally1 cars. The conditions can look good during reconnaissance and then turn out to be very demanding in the rally. It's not rough all of the time but you can get quite a lot of big ruts with many really soft and sandy places. But all four of our drivers can count on the experience they gained last year and have some idea of what to expect."Sebastien Ogier (Driver car 1)"I'm looking forward to returning to Kenya. Last year we had a really nice welcome and a great atmosphere. It was something special and different to what we are used to. To win was the cherry on the cake and it will be great to try to repeat that this year with a bit of knowledge of what to expect from the stages. We saw that it can be a very tough rally; I think nearly everybody had an issue at some point and we came back from over two minutes down to win. So it's definitely a rally where you have to never give up, and this year with the cars still being so new, we might have to be even more clever than before."Elfyn Evans (Driver car 33)"Even though we have experience from last year, it's always difficult to know exactly what we're going to face on an event like the Safari Rally. There's always an element of the unknown, and we saw last year that the conditions can change massively from one area to the next. Some sections can be very soft sand, some parts are much more hard-packed, and in other places it's very rough. It's a big challenge for the drivers, for the cars and for the engineers as well. I've had a good feeling with the GR YARIS Rally1 on gravel so far and the speed has been there. Safari requires something slightly different in terms of setup but hopefully that positive feeling will still carry forward."Kalle Rovanpera (Driver car 69)"I think the Safari Rally will be another interesting weekend. Of course Sardinia was maybe not as strong a rally for us as we wanted it to be, but I'm hoping that in Kenya maybe we will not lose so much time opening the road and we can try to have a good weekend. Last year, it was a good rally for us overall, we were just a bit unlucky to get stuck when we did at the end of Friday. This year we will try to avoid things like that and tackle the event in a better way, because we see a lot of difficult conditions there and things we don't normally see in modern rallies. So for sure it's a special place and you need to approach it a bit differently too."Please visit www.wrc.com for the latest. Copyright 2022 JCN Newswire. All rights reserved. (via SEAPRWire)

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