Category: SeaPRwire

Y-3, a Class 1 Innovative Drug injection, is used to alleviate neurological symptoms and dysfunction of daily activities caused by acute ischemic stroke. The Product has a clear mechanism of action, which is conducive to exerting brain cytoprotection effects. Meanwhile, the Product has a rapid anti-depression and anti-anxiety function, and is expected to become the first new type of brain cytoprotectant that treats both stroke and post-stroke depression. The product will enrich the cardio-cerebrovascular (including the central nervous system) pipeline of the Group. After approved for marketing in China, it is expected to meet the clinical needs of drug with both safety and efficacy, providing new treatment options to ischemic stroke patients in China. SHENZHEN, CHINA , Aug 24, 2023 – (ACN Newswire) – On August 24, China Medical System Holdings Limited (“CMS” or the “Group”) announced that the Group entered into a Collaboration Agreement (the “Agreement”) with Nanjing NeuroDawn Pharmaceutical Co. Ltd. (“NeuroDawn Pharmaceutical”), for anti-ischemic stroke brain cytoprotectant and class 1 innovative drug Y-3 injection (“Y-3 injection” or the “Product”), and gained an exclusive promotion right of the Product in Mainland China, Hong Kong Special Administrative Region and Macao Special Administrative Region. The term of the Agreement is permanent. Y-3 Injection is a Class 1 innovative drug – small molecule compound, which is used to alleviate neurological symptoms and dysfunction of daily activities caused by acute ischemic stroke. The mechanism of action of the Product is to dissociate PSD-95 and nNOS coupling and activate α2-GABAA receptors. With dual-target intervention at the same time and its clear mechanism of action, the Product is conducive to exerting brain cytoprotection effects. Meanwhile, the Product has a rapid anti-depression and anti-anxiety function, and is expected to become the first new type of brain cytoprotectant that treats both stroke and post-stroke depression. Stroke is a major non-communicable disease that seriously endangers the health of Chinese people. The overall lifetime risk of stroke in China is 39.9%, ranking the first in the world. The number of new cases of ischemic stroke in China was approximately 2.87 million in 2019, and the incidence rate substantially increased by 226.5% from 1990 to 2019, with a large patient population. Stroke has the characteristics of high disability rate and heavy economic burden. There is an urgent clinical need for evidence-based drugs to reduce family and social burdens. In January 2023, The Phase I clinical trial of the Product in China has been completed and the results showed a good overall safety. The Product is currently in the Phase II clinical trial in China. If approved for marketing in China, it will bring new treatment options to ischemic stroke patients in China, meet the clinical needs of drug with both safety and efficacy, and thus benefit the patients. CMS has been deeply engaged in the cardio-cerebrovascula/central nervous system therapeutic fields for years and possesses XinHuoSu (recombinant human brain natriuretic peptide for injection), Deanxit (flupentixol and melitracen tablets) and VALTOCO (the first diazepam nasal spray approved in China), etc. The Group has also established a compliant and efficient commercialization system in the cardio-cerebrovascular and central nervous system fields. In the future, the Group will continue to prioritize patients and clinical needs, strategically deploy more differentiated innovative drugs, and consistently expand the product portfolio in the Group’s advantageous specialty fields, benefiting a greater number of patients. For further detailed information, please visit the following link for the announcement, “Voluntary and Business Update Announcement Gaining Exclusive License of an Anti-Ischemic Stroke Class 1 Innovative Drug” issued by CMS on August 24 2023. About NEURODAWN PHARMACEUTICAL NeuroDawn Pharmaceutical, based in Nanjing, China, is an innovation and R&D-driven new drug company, focusing on the research and development of new drugs for central nervous system (CNS) diseases. NeuroDawn Pharmaceutical has established a comprehensive internal R&D platform, including chemical synthesis, biological screening, CMC (chemistry, manufacturing and control) development, DMPK (drug metabolism and pharmacokinetics) research, in vivo pharmacology research, toxicology research and clinical research, etc. In addition, NeuroDawn Pharmaceutical has integrated clinical resources for neurological diseases in China and established close collaboration with more than one hundred leading hospitals in China to provide comprehensive and complete technical services and professional guidance for clinical studies. About CMS CMS is a platform company linking pharmaceutical innovation and commercialization with strong product lifecycle management capability, dedicated to providing competitive products and services to meet unmet healthcare needs. CMS focuses on developing first- or best-in-class innovative products and has made the layout of about 30 differentiated pipeline products with strong market potential. CMS deeply engages in specialty therapeutic fields, and has developed proven commercialization capabilities, extensive networks and expert resources, resulting in leading academic and market positions for its major marketed products. CMS continues to strengthen the competitiveness of its cardio-cerebrovascular/gastroenterology business, and independently operated dermatology and medical aesthetic business, and ophthalmology business, whilst enhancing the scale and efficiency. CMS also entered into the Southeast Asian market to create new opportunities to further enhance the sustainable development of the Group. Media Contact Brand: China Medical System Holdings Ltd. Contact: CMS Investor Relations Email: ir@cms.net.cn Website: https://web.cms.net.cn/en/home/ Source: China Medical System Holdings Ltd.

August 20-24, Las Vegas Convention Center: Introducing O2O Integrated Products and Hosting On-Site Events Soeul, Korea, August 21, 2023 - (SEAPRWire) - GobizTown, an online exhibition platform operated by Ministry of SMEs(MSS) and Startups and Korea SMEs and Startups Agency (KOSME) will participate in ASD Market Week 2023, held at the Las Vegas Convention Center for four days from August 20th. ASD Market Week 2023 marks its 62nd anniversary this year and is North America's largest consumer goods expo. The SourceDirect section shows products that reflect various aspects of daily life, including home and lifestyle, food, beauty, and travel. At GobizKOREA Pavilion, 83 companies will present 167 products for visitors to explore. GobizTown (gobiztown.com) will present outstanding O2O technology at ASD Market Week 2023, introducing products from promising small and medium-sized enterprises (SMEs) in Korea. [caption id="" align="aligncenter" width="1470"] Special hall for GobizTown at ASD Market Week[/caption] Before the exhibition, interested visitors can access GobizTown to preview participating companies and the showcased product information. Subsequently, they can visit the offline booths to view and experience a wide range of products directly. After the exhibition, visitors can freely review products on GobizTown without any restrictions on time, location, or the number of attendees. They can also proceed with trade transactions with Korean companies. GobizTown has also organized a special event to commemorate booth visits. Finding the representative character Go-Bizi, hidden within GobizTown, participants will receive a Go-Bizi doll as gifts. Additionally, there will be a lucky draw, and 30 lucky winners will be awarded a secret box containing various excellent products from outstanding Korean SMEs. GobizTown stated, "Through our online virtual exhibition platform, we aim to provide visitors with vivid experiences of the showcased products and easily discover promising products from outstanding Korean SMEs. We anticipate that GobizTown will be an excellent virtual gateway for conducting trade transactions remotely." They added, "We have planned various experiences during the offline booths, including events and GobizTown interactions. We kindly request many visitors to participate in these exciting activities." Media contact Brand: GobizTown Contact: Ru Jieun Website: https://gobiztown.com/ SOURCE: GobizKOREA The article is provided by a third-party content provider. SEAPRWire ( https://www.seaprwire.com/ ) makes no warranties or representations in connection therewith. Any questions, please contact cs/at/SEAPRWire.com Sectors: Top Story, Daily News SEA PRWire: PR distribution in Southeast Asia (Hong Kong: AsiaExcite, EastMud; AsiaEase; Singapore: SEAChronicle, VOASG; NetDace; Thailand: SEAsiabiz, AccessTH; Indonesia: SEATribune, DailyBerita; Philippines: SEATickers, PHNotes; Malaysia: SEANewswire, KULPR; Vietnam: SEANewsDesk, PostVN)

On August 16, a high-profile tech meetup focusing on cloud-native open source projects was held at Singapore Institute of Technology NYP Building, organized by ByteDance Open Source in collaboration with the CNCF, Cloud Native Community. The tech meetup was organized with the active participation of many guests and participants from within and outside the industry. Keith Chan, Linux Foundation VP of APAC and President of CNCF Asia Pacific, gave the opening address at the event, focusing on the development of cloud-native technologies in the current market. He noted that motivations for organizations to adopt cloud native include improving resource efficiency, elasticity and availability, supporting multi-cloud and hybrid cloud deployments, and accelerating development. He emphasized the widespread adoption of cloud-native tools such as Kubernetes in the enterprise, mentioning success stories such as the practices of Zoom and Fidelity Investments. He also mentioned Gartner's predictions, noting that future AI applications will be based on containers and serverless technologies, while edge computing will get a boost. He emphasized the importance of certification and training in helping organizations adopt cloud-native technologies, mentioning the Kubernetes conformance certification program. CloudWeGo CloudWeGo is a set of microservices middleware developed and open sourced by ByteDance to solve the challenges delivered by the rapid growth of microservices and to meet increasingly complicated business requests. Based on this origin, CloudWeGo can be used to build enterprise-class cloud-native microservices architecture with common characteristics of high-performance, high-extensibility and high-reliability. For maintenance and support, CloudWeGo team follows a key principle of maintaining one set of code internally and externally, iterating them as a whole. We respond to every issue and PR from any single person as quickly as possible. We support any reasonable requests and technical issues from our enterprise in specialty and for free. CloudWeGo team values the real prosperity of the community. Up to now, there are more than 250 contributors coming from all over the world continuously contributing to the CloudWeGo community and more than 100 thousand individual users who are visiting the CloudWeGo website. Industry adoptions now include areas like Gaming, Security, Finance, E-commerce and AI with more than 30 enterprise users who have left their use cases on the corresponding issues. For more information, please visit: Website: https://www.cloudwego.io/ GitHub: https://github.com/cloudwego Kitex Kitex is CloudWeGo’s first open-source microservice framework, designed to empower developers in building high-performance microservices using Golang. It provides multiple protocols including thrift and gRPC and various features more than RPC such as service governance, observability. In the sharing, we introduce the strong extensiblity of Kitex. The design of interface in Kitex enables users to integrate customized modules like Codec, Transport and Middleware. It allows us to cooperate with the internal platforms in Bytedance and the open-source components in a very convenient way. For high performance, we introduced the optimization of Codec by more efficient memory management and a new solution Frugal based on JIT that does not need code generation and uses high performance assembly code in runtime. Kitex contributes to the open-source community with several extensions of open-source components. We shared some use cases including opentelemetry for tracing each rpc with detailed events, proxyless mode with Istio for traffic management and Generic call that is suitable for building API gateways. For enterprise support, we assisted more than 10 enterprise users to adopt Kitex in the production environment and achieved high performance and stability in their systems. For more information, please visit: Website: github.com/cloudwego/kitex Kitex-contrib: github.com/kitex-contrib ByConity ByConity is an open source Data Warehouse system designed for modern IT architecture changes and, it is designed with a Cloud Native architecture. It provides excellent query and write performance while meeting the needs of Data Warehouse users for resource elastic volume expansion and contraction, read and write separation, resource isolation, and strong data consistency. ByConity uses a large number of mature OLAP technologies, such as column storage engine, MPP execution, intelligent query optimization, vectorization execution, Codegen, indexing, and data compression. It also makes technical innovations for the particularity of cloud scenarios and storage and calculation separation architectures. In this speech, there is an introduction to ByConity and best practices and recommended scenarios. KubeWharf KubeWharf is a collection of open-source tools from ByteDance built on Kubernetes. It aims to provide solutions to key challenges of large-scale cloud-native infrastructure such as scalability, stability, multi-tenancy isolation, resource efficiency and observability. Currently, there are 6 open-source projects in KubeWharf. This time we introduced KubeAdmiral - Enhanced Kubernetes Federation. KubeAdmiral is a multi-cluster management system for Kubernetes, developed based on Kubernetes Federation v2. KubeAdmiral allows users to easily manage multiple Kubernetes clusters and propagate workloads to member clusters through a unified interface and resource pool. With its rich and scalable scheduling and distribution framework, KubeAdmiral supports a diverse set of use cases including but not limited to: Dynamic replica distribution based on real-time resource utilisation. Cross-cluster disaster recovery. Configurable scheduling profiles with a rich set of scheduling plugins. Override policies. Automatic propagation of dependencies with follower scheduling. Status aggregation of member cluster resources. Scalability, stability and user experience enhancements. Internally at ByteDance, KubeAdmiral manages 210,000 nodes and supports 100,000+ microservices. It has been officially open-source in 2023. ByConity is an open source Data Warehouse system designed for modern IT architecture changes and, it is designed with a Cloud Native architecture. It provides excellent query and write performance while meeting the needs of Data Warehouse users for resource elastic volume expansion and contraction, read and write separation, resource isolation, and strong data consistency. ByConity uses a large number of mature OLAP technologies, such as column storage engine, MPP execution, intelligent query optimization, vectorization execution, Codegen, indexing, and data compression. It also makes technical innovations for the particularity of cloud scenarios and storage and calculation separation architectures. In this speech, there is an introduction to ByConity and best practices and recommended scenarios. KubeWharf KubeWharf is a collection of open-source tools from ByteDance built on Kubernetes. It aims to provide solutions to key challenges of large-scale cloud-native infrastructure such as scalability, stability, multi-tenancy isolation, resource efficiency and observability. Currently, there are 6 open-source projects in KubeWharf. This time we introduced KubeAdmiral - Enhanced Kubernetes Federation. KubeAdmiral is a multi-cluster management system for Kubernetes, developed based on Kubernetes Federation v2. KubeAdmiral allows users to easily manage multiple Kubernetes clusters and propagate workloads to member clusters through a unified interface and resource pool. With its rich and scalable scheduling and distribution framework, KubeAdmiral supports a diverse set of use cases including but not limited to: Dynamic replica distribution based on real-time resource utilisation. Cross-cluster disaster recovery. Configurable scheduling profiles with a rich set of scheduling plugins. Override policies. Automatic propagation of dependencies with follower scheduling. Status aggregation of member cluster resources. Scalability, stability and user experience enhancements. Internally at ByteDance, KubeAdmiral manages 210,000 nodes and supports 100,000+ microservices. It has been officially open-source in 2023. This technical meetup provides an excellent opportunity for industry players to deeply communicate, share experiences, learn best practices, and further promote the innovation and development of cloud-native open source projects. We sincerely welcome industry players to participate in this event and join hands with us to create a more brilliant future for cloud-native open source projects. The Cloud Native meetup is a key component of the 2023 Singapore International Open Source Festival (IOSF) conference, designed to provide attendees with an in-depth understanding of cloud native technologies. 2023 Singapore IOSF is scheduled to be held on December 7-8, 2023 at Singapore Institute of Technology, and will bring together lecturers, vendors, and partners from various fields to discuss cutting-edge topics and innovations in the open source space. We cordially invite all lecturers, vendors and potential partners to come and participate in this event. During the conference, you will have the opportunity to have in-depth communication and interaction with industry leaders, technical experts and peers, and share the latest technology trends and best practices. At the same time, we also welcome interested partners to contact us by email to further discuss cooperation and investment matters. We look forward to participating and creating the 2023 Singapore International Open Source Festival with you. For more details of cooperation, please contact us：tonytang@ostechhome.com

New York, NY, August 11, 2023 – (SEAPRWire) – Australian cricket legend Shane Watson has been named as a Global Brand Ambassador for leading trading platform Main Group FX. The partnership sees Watson – first selected for Australia in 2002 – work with the group as it aims to expand its global marketing efforts. Brokered by Nick Hunter of P11, the agreement will see the cricketer appear in international marketing campaigns and participate in social media giveaways, in a bid to engage with fans and promote Main Group FX’s commitment to trust, reliability and industry leading services. Karim Farag, CEO of Main Group FX commented: “We are thrilled to partner with a world-class talent like Shane Watson!” “We believe that Shane is an undisputed legend in the cricketing world and having him on our team will help beyond brand awareness. He has given us insight on the Australian mindset, helping us provide a better support to our clients.” A prominent member from Australia’s test “Golden Era” and one of only seven cricketers to have taken over 250 wickets and scored over 10,000 runs in international cricket, there is very little Watson did not achieve in his career. Representing his country for over a decade in each of the three formats, he won two Cricket World Cups, two ICC Champions Trophies and has an Ashes series win to his name, as well as holding the all-time record for weeks consecutively spent as the world’s number 1 all-rounder in T20I cricket, holding the title from 2011 to early 2014. Away from the international stage, Watson also has one PSL title and two IPL titles to his name – while on an individual level being named PSL MVP once and IPL MVP on two occasions – playing his final IPL season in 2020 when he retired from his illustrious career in the sport. “I’m really excited to represent the team at Main Group FX, it’s one of the fastest-growing trading platforms right now,” said Watson. “They have a very professional team behind, offering unique industry products.” Social Links Facebook: https://www.facebook.com/maingroupfx/ Twitter: https://twitter.com/maingroupfx/ Instagram: https://www.instagram.com/maingroupfx/ LinkedIn: https://www.linkedin.com/company/main-group-fx/ Media Contact Brand: Main Group FX Contact: Nick Hunter Website: www.maingroupfx.com.au SOURCE: Main Group FX The article is provided by a third-party content provider. SEAPRWire ( https://www.seaprwire.com/ ) makes no warranties or representations in connection therewith. Any questions, please contact cs/at/SEAPRWire.com Sectors: Top Story, Daily News SEA PRWire: PR distribution in Southeast Asia (Hong Kong: AsiaExcite, EastMud; AsiaEase; Singapore: SEAChronicle, VOASG; NetDace; Thailand: SEAsiabiz, AccessTH; Indonesia: SEATribune, DailyBerita; Philippines: SEATickers, PHNotes; Malaysia: SEANewswire, KULPR; Vietnam: SEANewsDesk, PostVN)